The RSPO3 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to R-Spondin 3, and RSPO3. This antibody recognizes Human antigen. The RSPO3 Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway